Computational modeling of ovarian cancer dynamics suggests optimal strategies for therapy and screening

High-grade serous tubo-ovarian carcinoma (HGSC) is a major cause of cancer-related death. Treatment is not uniform, with some patients undergoing primary debulking surgery followed by chemotherapy (PDS) and others being treated directly with chemotherapy and only having surgery after three to four c...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Gu, Shengqing, Lheureux, Stephanie, Sayad, Azin, Cybulska, Paulina, Hogen, Liat, Vyarvelska, Iryna, Tu, Dongsheng, Parulekar, Wendy R., Nankivell, Matthew, Kehoe, Sean, Chi, Dennis S., Levine, Douglas A., Bernardini, Marcus Q., Rosen, Barry, Oza, Amit, Brown, Myles, Neel, Benjamin G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2021
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237655/
https://ncbi.nlm.nih.gov/pubmed/34161278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2026663118
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