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Tailoring Ovarian Cancer Treatment: Implications of BRCA1/2 Mutations
High grade serous ovarian cancer (HGSOC) is the most common epithelial ovarian cancer, harbouring more than 20% germline or somatic mutations in the tumour suppressor genes BRCA1 and BRCA2. These genes are involved in both DNA damage repair process via homologous recombination (HR) and transcription...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6468364/ https://ncbi.nlm.nih.gov/pubmed/30909618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11030416 |
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