Computational modeling of ovarian cancer dynamics suggests optimal strategies for therapy and screening

High-grade serous tubo-ovarian carcinoma (HGSC) is a major cause of cancer-related death. Treatment is not uniform, with some patients undergoing primary debulking surgery followed by chemotherapy (PDS) and others being treated directly with chemotherapy and only having surgery after three to four c...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gu, Shengqing, Lheureux, Stephanie, Sayad, Azin, Cybulska, Paulina, Hogen, Liat, Vyarvelska, Iryna, Tu, Dongsheng, Parulekar, Wendy R., Nankivell, Matthew, Kehoe, Sean, Chi, Dennis S., Levine, Douglas A., Bernardini, Marcus Q., Rosen, Barry, Oza, Amit, Brown, Myles, Neel, Benjamin G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237655/
https://ncbi.nlm.nih.gov/pubmed/34161278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2026663118
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