Computational modeling of ovarian cancer dynamics suggests optimal strategies for therapy and screening

High-grade serous tubo-ovarian carcinoma (HGSC) is a major cause of cancer-related death. Treatment is not uniform, with some patients undergoing primary debulking surgery followed by chemotherapy (PDS) and others being treated directly with chemotherapy and only having surgery after three to four c...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Gu, Shengqing, Lheureux, Stephanie, Sayad, Azin, Cybulska, Paulina, Hogen, Liat, Vyarvelska, Iryna, Tu, Dongsheng, Parulekar, Wendy R., Nankivell, Matthew, Kehoe, Sean, Chi, Dennis S., Levine, Douglas A., Bernardini, Marcus Q., Rosen, Barry, Oza, Amit, Brown, Myles, Neel, Benjamin G.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2021
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237655/
https://ncbi.nlm.nih.gov/pubmed/34161278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2026663118
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