Ceramide synthase 2-C(24:1)-ceramide axis limits the metastatic potential of ovarian cancer cells

Regulation of sphingolipid metabolism plays a role in cellular homeostasis, and dysregulation of these pathways is involved in cancer progression. Previously, our reports identified ceramide as an anti-metastatic lipid. In the present study, we investigated the biochemical alterations in ceramide-ce...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Zhang, Xuewei, Sakamoto, Wataru, Canals, Daniel, Ishibashi, Masumi, Matsuda, Masaya, Nishida, Kentaro, Toyoshima, Masafumi, Shigeta, Shogo, Taniguchi, Makoto, Senkal, Can E., Okazaki, Toshiro, Yaegashi, Nobuo, Hannun, Yusuf A., Nabe, Takeshi, Kitatani, Kazuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237407/
https://ncbi.nlm.nih.gov/pubmed/33423335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202001504RR
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