The Role of Notch3 Signaling in Cancer Stemness and Chemoresistance: Molecular Mechanisms and Targeting Strategies

Aberrant Notch signaling profoundly affects cancer progression. Especially the Notch3 receptor was found to be dysregulated in cancer, where its expression is correlated with worse clinicopathological features and poor prognosis. The activation of Notch3 signaling is closely related to the activatio...

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Опубликовано в: :Front Mol Biosci
Главные авторы: Xiu, Mengxi, Wang, Yongbo, Li, Baoli, Wang, Xifeng, Xiao, Fan, Chen, Shoulin, Zhang, Lieliang, Zhou, Bin, Hua, Fuzhou
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Molecular Biosciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237348/
https://ncbi.nlm.nih.gov/pubmed/34195229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.694141
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