The Role of Notch3 Signaling in Cancer Stemness and Chemoresistance: Molecular Mechanisms and Targeting Strategies

Aberrant Notch signaling profoundly affects cancer progression. Especially the Notch3 receptor was found to be dysregulated in cancer, where its expression is correlated with worse clinicopathological features and poor prognosis. The activation of Notch3 signaling is closely related to the activatio...

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Foilsithe in:Front Mol Biosci
Main Authors: Xiu, Mengxi, Wang, Yongbo, Li, Baoli, Wang, Xifeng, Xiao, Fan, Chen, Shoulin, Zhang, Lieliang, Zhou, Bin, Hua, Fuzhou
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2021
Ábhair:
Molecular Biosciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237348/
https://ncbi.nlm.nih.gov/pubmed/34195229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.694141
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