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The Role of Notch3 Signaling in Cancer Stemness and Chemoresistance: Molecular Mechanisms and Targeting Strategies

Aberrant Notch signaling profoundly affects cancer progression. Especially the Notch3 receptor was found to be dysregulated in cancer, where its expression is correlated with worse clinicopathological features and poor prognosis. The activation of Notch3 signaling is closely related to the activatio...

詳細記述

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書誌詳細
出版年:Front Mol Biosci
主要な著者: Xiu, Mengxi, Wang, Yongbo, Li, Baoli, Wang, Xifeng, Xiao, Fan, Chen, Shoulin, Zhang, Lieliang, Zhou, Bin, Hua, Fuzhou
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237348/
https://ncbi.nlm.nih.gov/pubmed/34195229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2021.694141
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