The CRBN, CUL4A and DDB1 Expression Predicts the Response to Immunomodulatory Drugs and Survival of Multiple Myeloma Patients

Immunomodulatory drugs (IMiDs) are effective in the treatment of multiple myeloma (MM), myelodysplastic syndrome with deletion of chromosome 5q and other haematological malignancies. Recent studies showed that IMiDs bind to cereblon (CRBN), a substrate receptor of the CRL4–CRBN complex, to induce th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Barankiewicz, Joanna, Szumera-Ciećkiewicz, Anna, Salomon-Perzyński, Aleksander, Wieszczy, Paulina, Malenda, Agata, Garbicz, Filip, Prochorec-Sobieszek, Monika, Misiewicz-Krzemińska, Irena, Juszczyński, Przemysław, Lech-Marańda, Ewa
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8235391/
https://ncbi.nlm.nih.gov/pubmed/34207079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm10122683
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados