A carregar...
CUL4-DDB1-CRBN E3 Ubiquitin Ligase Regulates Proteostasis of ClC-2 Chloride Channels: Implication for Aldosteronism and Leukodystrophy
Voltage-gated ClC-2 channels are essential for chloride homeostasis. Complete knockout of mouse ClC-2 leads to testicular degeneration and neuronal myelin vacuolation. Gain-of-function and loss-of-function mutations in the ClC-2-encoding human CLCN2 gene are linked to the genetic diseases aldosteron...
Na minha lista:
| Publicado no: | Cells |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7348978/ https://ncbi.nlm.nih.gov/pubmed/32466489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061332 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|