Persistence of CRISPR/Cas9 gene edited hematopoietic stem cells following transplantation: A systematic review and meta‐analysis of preclinical studies

Gene editing blood‐derived cells is an attractive approach to cure selected monogenic diseases but remains experimental. A systematic search of preclinical controlled studies is needed to determine the persistence of edited cells following reinfusion. All studies identified in our systematic search...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Stem Cells Transl Med
Autori principali: Maganti, Harinad B., Bailey, Adrian J. M., Kirkham, Aidan M., Shorr, Risa, Pineault, Nicolas, Allan, David S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2021
Soggetti:
Concise Reviews
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8235122/
https://ncbi.nlm.nih.gov/pubmed/33666363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.20-0520
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