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CRISPR/Cas9 genome editing in human hematopoietic stem cells

Genome editing via homologous recombination (HR) (gene targeting) in human hematopoietic stem cells (HSCs) has the power to reveal gene–function relationships and potentially transform curative hematological gene and cell therapies. However, there are no comprehensive and reproducible protocols for...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Protoc
Prif Awduron: Bak, Rasmus O, Dever, Daniel P, Porteus, Matthew H
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826598/
https://ncbi.nlm.nih.gov/pubmed/29370156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2017.143
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