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CRISPR/Cas9 genome editing in human hematopoietic stem cells

Genome editing via homologous recombination (HR) (gene targeting) in human hematopoietic stem cells (HSCs) has the power to reveal gene–function relationships and potentially transform curative hematological gene and cell therapies. However, there are no comprehensive and reproducible protocols for...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Protoc
Päätekijät: Bak, Rasmus O, Dever, Daniel P, Porteus, Matthew H
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826598/
https://ncbi.nlm.nih.gov/pubmed/29370156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2017.143
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