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Optimized immunofluorescence staining protocol for imaging germinal centers in secondary lymphoid tissues of vaccinated mice

Location of immune cells that form the germinal center reaction within secondary lymphoid tissues can be characterized using confocal microscopy. Here, we present an optimized immunofluorescence staining protocol to image germinal center structures in fixed/frozen spleen sections from ChAdOx1 nCoV-1...

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Bibliografiske detaljer
Udgivet i:STAR Protoc
Main Authors: Fra-Bido, Sigrid, Walker, Simon A., Innocentin, Silvia, Linterman, Michelle A.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233161/
https://ncbi.nlm.nih.gov/pubmed/34195671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100499
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