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Optimized immunofluorescence staining protocol for imaging germinal centers in secondary lymphoid tissues of vaccinated mice

Location of immune cells that form the germinal center reaction within secondary lymphoid tissues can be characterized using confocal microscopy. Here, we present an optimized immunofluorescence staining protocol to image germinal center structures in fixed/frozen spleen sections from ChAdOx1 nCoV-1...

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Detalhes bibliográficos
Publicado no:STAR Protoc
Main Authors: Fra-Bido, Sigrid, Walker, Simon A., Innocentin, Silvia, Linterman, Michelle A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8233161/
https://ncbi.nlm.nih.gov/pubmed/34195671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100499
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