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Ageing promotes early T follicular helper cell differentiation by modulating expression of RBPJ

Ageing profoundly changes our immune system and is thought to be a driving factor in the morbidity and mortality associated with infectious disease in older people. We have previously shown that the impaired immunity to vaccination that occurs in aged individuals is partly attributed to the effect o...

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Dettagli Bibliografici
Pubblicato in:Aging Cell
Autori principali: Webb, Louise M. C., Fra‐Bido, Sigrid, Innocentin, Silvia, Matheson, Louise S., Attaf, Noudjoud, Bignon, Alexandre, Novarino, Julien, Fazilleau, Nicolas, Linterman, Michelle A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811847/
https://ncbi.nlm.nih.gov/pubmed/33387451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13295
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