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Functional Characterization of the Dopaminergic Psychostimulant Sydnocarb as an Allosteric Modulator of the Human Dopamine Transporter

The dopamine transporter (DAT) serves a critical role in controlling dopamine (DA)-mediated neurotransmission by regulating the clearance of DA from the synapse and extrasynaptic regions and thereby modulating DA action at postsynaptic DA receptors. Major drugs of abuse such as amphetamine and cocai...

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Foilsithe in:Biomedicines
Main Authors: Aggarwal, Shaili, Cheng, Mary Hongying, Salvino, Joseph M., Bahar, Ivet, Mortensen, Ole Valente
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2021
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8227285/
https://ncbi.nlm.nih.gov/pubmed/34199621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9060634
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