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Functional Characterization of the Dopaminergic Psychostimulant Sydnocarb as an Allosteric Modulator of the Human Dopamine Transporter

The dopamine transporter (DAT) serves a critical role in controlling dopamine (DA)-mediated neurotransmission by regulating the clearance of DA from the synapse and extrasynaptic regions and thereby modulating DA action at postsynaptic DA receptors. Major drugs of abuse such as amphetamine and cocai...

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Dettagli Bibliografici
Pubblicato in:Biomedicines
Autori principali: Aggarwal, Shaili, Cheng, Mary Hongying, Salvino, Joseph M., Bahar, Ivet, Mortensen, Ole Valente
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8227285/
https://ncbi.nlm.nih.gov/pubmed/34199621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9060634
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