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Allosteric modulation of human dopamine transporter activity under conditions promoting its dimerization

The human dopamine (DA) transporter (hDAT) is a key regulator of neurotransmission and a target for antidepressants and addictive drugs. Despite the recent resolution of dDAT structures from Drosophila melanogaster, complete understanding of its mechanism of function and even information on its biol...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Cheng, Mary Hongying, Garcia-Olivares, Jennie, Wasserman, Steven, DiPietro, Jennifer, Bahar, Ivet
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535022/
https://ncbi.nlm.nih.gov/pubmed/28584050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.763565
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