Identification of a Novel Allosteric Modulator of the Human Dopamine Transporter

The dopamine transporter (DAT) serves a pivotal role in controlling dopamine (DA)-mediated neurotransmission by clearing DA from synaptic and perisynaptic spaces and controlling its action at postsynaptic DA receptors. Major drugs of abuse such as amphetamine and cocaine interact with DAT to mediate...

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Publicado en:ACS Chem Neurosci
Autores principales: Aggarwal, Shaili, Liu, Xiaonan, Rice, Caitlyn, Menell, Paul, Clark, Philip J., Paparoidamis, Nicholas, Xiao, You-cai, Salvino, Joseph M., Fontana, Andréia C. K., España, Rodrigo A., Kortagere, Sandhya, Mortensen, Ole V.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703927/
https://ncbi.nlm.nih.gov/pubmed/31184115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.9b00262
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