Identification of a Novel Allosteric Modulator of the Human Dopamine Transporter

The dopamine transporter (DAT) serves a pivotal role in controlling dopamine (DA)-mediated neurotransmission by clearing DA from synaptic and perisynaptic spaces and controlling its action at postsynaptic DA receptors. Major drugs of abuse such as amphetamine and cocaine interact with DAT to mediate...

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Pubblicato in:ACS Chem Neurosci
Autori principali: Aggarwal, Shaili, Liu, Xiaonan, Rice, Caitlyn, Menell, Paul, Clark, Philip J., Paparoidamis, Nicholas, Xiao, You-cai, Salvino, Joseph M., Fontana, Andréia C. K., España, Rodrigo A., Kortagere, Sandhya, Mortensen, Ole V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6703927/
https://ncbi.nlm.nih.gov/pubmed/31184115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.9b00262
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