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Gene Dosage- and Age-Dependent Differential Transcriptomic Changes in the Prefrontal Cortex of Shank2-Mutant Mice

Shank2 is an abundant postsynaptic scaffolding protein that is known to regulate excitatory synapse assembly and synaptic transmission and has been implicated in various neurodevelopmental disorders, including autism spectrum disorders (ASD). Previous studies on Shank2-mutant mice provided mechanist...

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Detalles Bibliográficos
Publicado en:Front Mol Neurosci
Main Authors: Lee, Seungjoon, Kang, Hyojin, Jung, Hwajin, Kim, Eunjoon, Lee, Eunee
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8226033/
https://ncbi.nlm.nih.gov/pubmed/34177464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2021.683196
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