Cell-Type-Specific Shank2 Deletion in Mice Leads to Differential Synaptic and Behavioral Phenotypes

Shank2 is an excitatory postsynaptic scaffolding protein implicated in synaptic regulation and psychiatric disorders including autism spectrum disorders. Conventional Shank2-mutant (Shank2(−/−)) mice display several autistic-like behaviors, including social deficits, repetitive behaviors, hyperactiv...

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Vydáno v:J Neurosci
Hlavní autoři: Kim, Ryunhee, Kim, Jihye, Chung, Changuk, Ha, Seungmin, Lee, Seungjoon, Lee, Eunee, Yoo, Ye-Eun, Kim, Woohyun, Shin, Wangyong, Kim, Eunjoon
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2018
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596028/
https://ncbi.nlm.nih.gov/pubmed/29572432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2684-17.2018
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