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Cell-Type-Specific Shank2 Deletion in Mice Leads to Differential Synaptic and Behavioral Phenotypes
Shank2 is an excitatory postsynaptic scaffolding protein implicated in synaptic regulation and psychiatric disorders including autism spectrum disorders. Conventional Shank2-mutant (Shank2(−/−)) mice display several autistic-like behaviors, including social deficits, repetitive behaviors, hyperactiv...
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| Veröffentlicht in: | J Neurosci |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Society for Neuroscience
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6596028/ https://ncbi.nlm.nih.gov/pubmed/29572432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2684-17.2018 |
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