Cell-Type-Specific Shank2 Deletion in Mice Leads to Differential Synaptic and Behavioral Phenotypes

Shank2 is an excitatory postsynaptic scaffolding protein implicated in synaptic regulation and psychiatric disorders including autism spectrum disorders. Conventional Shank2-mutant (Shank2(−/−)) mice display several autistic-like behaviors, including social deficits, repetitive behaviors, hyperactiv...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Kim, Ryunhee, Kim, Jihye, Chung, Changuk, Ha, Seungmin, Lee, Seungjoon, Lee, Eunee, Yoo, Ye-Eun, Kim, Woohyun, Shin, Wangyong, Kim, Eunjoon
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
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Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6596028/
https://ncbi.nlm.nih.gov/pubmed/29572432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2684-17.2018
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