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Transcriptome analyses suggest minimal effects of Shank3 dosage on directional gene expression changes in the mouse striatum
Both deletions and duplications of the SH3 and multiple ankyrin repeat domains 3 (SHANK3) gene, encoding excitatory postsynaptic scaffolds, are causally associated with various brain disorders, suggesting that proper Shank3 dosage is critical for normal brain development and function. In addition to...
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| Veröffentlicht in: | Anim Cells Syst (Seoul) |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6711111/ https://ncbi.nlm.nih.gov/pubmed/31489248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19768354.2019.1595142 |
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