Integrative Brain Transcriptome Analysis Reveals Region-Specific and Broad Molecular Changes in Shank3-Overexpressing Mice

Variants of the SH3 and multiple ankyrin repeat domain 3 (SHANK3) gene, encoding excitatory postsynaptic core scaffolding proteins, are causally associated with numerous neurodevelopmental and neuropsychiatric disorders, including autism spectrum disorder (ASD), bipolar disorder, intellectual disabi...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Jin, Chunmei, Kang, Hyojin, Ryu, Jae Ryun, Kim, Shinhyun, Zhang, Yinhua, Lee, Yeunkum, Kim, Yoonhee, Han, Kihoon
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127286/
https://ncbi.nlm.nih.gov/pubmed/30233305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00250
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