CD52-targeted depletion by Alemtuzumab ameliorates allergic airway hyperreactivity and lung inflammation

Allergic asthma is a chronic inflammatory disorder associated with airway hyperreactivity (AHR) whose global prevalence is increasing at an alarming rate. Group 2 innate lymphoid cells (ILC2s) and T helper 2 (T(H)2) cells are producers of type 2 cytokines, which may contribute to development of AHR....

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Dettagli Bibliografici
Pubblicato in:Mucosal Immunol
Autori principali: Shafiei-Jahani, Pedram, Helou, Doumet Georges, Hurrell, Benjamin P., Galle-Treger, Lauriane, Howard, Emily, Quach, Christine, Painter, Jacob D., Fung, Marshall, Lo, Richard, Allayee, Hooman, Akbari, Omid
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2021
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8225558/
https://ncbi.nlm.nih.gov/pubmed/33731828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-021-00388-5
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