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TNFR2 Signaling Enhances ILC2 Survival, Function, and Induction of Airway Hyperreactivity
Group 2 innate lymphoid cells (ILC2s) can initiate pathologic inflammation in allergic asthma by secreting copious amounts of type 2 cytokines, promoting lung eosinophilia and airway hyperreactivity (AHR), a cardinal feature of asthma. We discovered that the TNF/TNFR2 axis is a central immune checkp...
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| 發表在: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6940205/ https://ncbi.nlm.nih.gov/pubmed/31875557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.11.102 |
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