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Targeted Inactivation of Rin3 Increases Trabecular Bone Mass by Reducing Bone Resorption and Favouring Bone Formation

Common genetic variants at the RIN3 locus on chromosome 14q32 predispose to Paget’s disease of bone (PDB) but the mechanisms by which they do so are unknown. Here, we analysed the skeletal phenotype of female mice with targeted inactivation of the mouse Rin3 gene (Rin3(−/−)) as compared with wild-ty...

詳細記述

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書誌詳細
出版年:Calcif Tissue Int
主要な著者: Vallet, Mahéva, Sophocleous, Antonia, Törnqvist, Anna E., Azfer, Asim, Hof, Rob van’t, Albagha, Omar ME, Ralston, Stuart H.
フォーマット: Artigo
言語:Inglês
出版事項: Springer US 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8225545/
https://ncbi.nlm.nih.gov/pubmed/33725152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-021-00827-2
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