Targeted sequencing of the Paget's disease associated 14q32 locus identifies several missense coding variants in RIN3 that predispose to Paget's disease of bone

Paget's disease of bone (PDB) is a common disorder with a strong genetic component characterized by increased but disorganized bone remodelling. Previous genome-wide association studies identified a locus on chromosome 14q32 tagged by rs10498635 which was significantly associated with susceptib...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Hum Mol Genet
Autori principali: Vallet, Mahéva, Soares, Dinesh C., Wani, Sachin, Sophocleous, Antonia, Warner, Jon, Salter, Donald M., Ralston, Stuart H., Albagha, Omar M.E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2015
Soggetti:
Association Studies Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424954/
https://ncbi.nlm.nih.gov/pubmed/25701875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv068
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi