A carregar...

Physiologically Based Pharmacokinetic Modelling of Cabozantinib to Simulate Enterohepatic Recirculation, Drug–Drug Interaction with Rifampin and Liver Impairment

Cabozantinib (CAB) is a receptor tyrosine kinase inhibitor approved for the treatment of several cancer types. Enterohepatic recirculation (EHC) of the substance is assumed but has not been further investigated yet. CAB is mainly metabolized via CYP3A4 and is susceptible for drug–drug interactions (...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Gerner, Bettina, Scherf-Clavel, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8224782/
https://ncbi.nlm.nih.gov/pubmed/34067429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics13060778
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!