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Genetic engineering of porcine endothelial cell lines for evaluation of human-to-pig xenoreactive immune responses

Xenotransplantation (cross-species transplantation) using genetically-engineered pig organs offers a potential solution to address persistent organ shortage. Current evaluation of porcine genetic modifications is to monitor the nonhuman primate immune response and survival after pig organ xenotransp...

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Publicat a:Sci Rep
Autors principals: Li, Ping, Walsh, Julia R., Lopez, Kevin, Isidan, Abdulkadir, Zhang, Wenjun, Chen, Angela M., Goggins, William C., Higgins, Nancy G., Liu, Jianyun, Brutkiewicz, Randy R., Smith, Lester J., Hara, Hidetaka, Cooper, David K. C., Ekser, Burcin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222275/
https://ncbi.nlm.nih.gov/pubmed/34162938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92543-y
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