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REGULATION OF HUMAN PLATELET AGGREGATION BY GENETICALLY MODIFIED PIG ENDOTHELIAL CELLS AND THROMBIN INHIBITION
BACKGROUND: Coagulation disorders remain barriers to successful pig-to-primate organ xenotransplantation. In vitro, we investigated the impact of pig genetic modifications on human platelet aggregation in response to pig aortic endothelial cells (pAEC). METHODS: In comparison to human (h)AEC and wil...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4010578/ https://ncbi.nlm.nih.gov/pubmed/24188473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12073 |
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