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PERSPECTIVES ON THE OPTIMAL GENETICALLY-ENGINEERED PIG IN 2018 FOR INITIAL CLINICAL TRIALS OF KIDNEY OR HEART XENOTRANSPLANTATION
For a clinical trial today, what might realistically be the optimal pig among those currently available? Deletion of expression of the 3 pig carbohydrate antigens against which humans have natural (preformed) antibodies (triple-knockout [TKO] pigs) should form the basis of any clinical trial. Howeve...
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| Published in: | Transplantation |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6249080/ https://ncbi.nlm.nih.gov/pubmed/30247446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000002443 |
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