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Genetic engineering of porcine endothelial cell lines for evaluation of human-to-pig xenoreactive immune responses

Xenotransplantation (cross-species transplantation) using genetically-engineered pig organs offers a potential solution to address persistent organ shortage. Current evaluation of porcine genetic modifications is to monitor the nonhuman primate immune response and survival after pig organ xenotransp...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Li, Ping, Walsh, Julia R., Lopez, Kevin, Isidan, Abdulkadir, Zhang, Wenjun, Chen, Angela M., Goggins, William C., Higgins, Nancy G., Liu, Jianyun, Brutkiewicz, Randy R., Smith, Lester J., Hara, Hidetaka, Cooper, David K. C., Ekser, Burcin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222275/
https://ncbi.nlm.nih.gov/pubmed/34162938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92543-y
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