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EXPRESSION OF NeuGc ON PIG CORNEAS AND ITS POTENTIAL SIGNIFICANCE IN PIG CORNEAL XENOTRANSPLANTATION

PURPOSE: Pigs expressing neither galactose-α1,3-galactose (Gal) nor N-glycolylneuraminic acid (NeuGc) take xenotransplantation one step closer to the clinic. Our aims were (i) to document the lack of NeuGc expression on corneas and aortas, and cultured endothelial cells (aortic [AECs]; corneal [CECs...

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Detalhes bibliográficos
Publicado no:Cornea
Main Authors: Lee, Whayoung, Miyagawa, Yuko, Long, Cassandra, Ekser, Burcin, Walters, Eric, Ramsoondar, Jagdeece, Ayares, David, Tector, A. Joseph, Cooper, David K. C., Hara, Hidetaka
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847538/
https://ncbi.nlm.nih.gov/pubmed/26418433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ICO.0000000000000635
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