EXPRESSION OF NeuGc ON PIG CORNEAS AND ITS POTENTIAL SIGNIFICANCE IN PIG CORNEAL XENOTRANSPLANTATION

PURPOSE: Pigs expressing neither galactose-α1,3-galactose (Gal) nor N-glycolylneuraminic acid (NeuGc) take xenotransplantation one step closer to the clinic. Our aims were (i) to document the lack of NeuGc expression on corneas and aortas, and cultured endothelial cells (aortic [AECs]; corneal [CECs...

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Dettagli Bibliografici
Pubblicato in:Cornea
Autori principali: Lee, Whayoung, Miyagawa, Yuko, Long, Cassandra, Ekser, Burcin, Walters, Eric, Ramsoondar, Jagdeece, Ayares, David, Tector, A. Joseph, Cooper, David K. C., Hara, Hidetaka
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847538/
https://ncbi.nlm.nih.gov/pubmed/26418433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ICO.0000000000000635
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