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EXPRESSION OF NeuGc ON PIG CORNEAS AND ITS POTENTIAL SIGNIFICANCE IN PIG CORNEAL XENOTRANSPLANTATION

PURPOSE: Pigs expressing neither galactose-α1,3-galactose (Gal) nor N-glycolylneuraminic acid (NeuGc) take xenotransplantation one step closer to the clinic. Our aims were (i) to document the lack of NeuGc expression on corneas and aortas, and cultured endothelial cells (aortic [AECs]; corneal [CECs...

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Vydáno v:Cornea
Hlavní autoři: Lee, Whayoung, Miyagawa, Yuko, Long, Cassandra, Ekser, Burcin, Walters, Eric, Ramsoondar, Jagdeece, Ayares, David, Tector, A. Joseph, Cooper, David K. C., Hara, Hidetaka
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847538/
https://ncbi.nlm.nih.gov/pubmed/26418433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ICO.0000000000000635
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