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Regulatory Role of mTOR Signaling in Exosome Secretion and Osteogenic Changes in Smooth Muscle Cells Lacking Acid Ceramidase Gene
Acid ceramidase (murine gene code: Asah1) (50 kDa) belongs to N-terminal nucleophile hydrolase family. This enzyme is located in the lysosome, which mediates conversion of ceramide (CER) into sphingosine and free fatty acids at acidic pH. CER plays an important role in intracellular sphingolipid met...
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| Udgivet i: | FASEB J |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8221173/ https://ncbi.nlm.nih.gov/pubmed/34143450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202100385R |
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