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Regulatory Role of mTOR Signaling in Exosome Secretion and Osteogenic Changes in Smooth Muscle Cells Lacking Acid Ceramidase Gene

Acid ceramidase (murine gene code: Asah1) (50 kDa) belongs to N-terminal nucleophile hydrolase family. This enzyme is located in the lysosome, which mediates conversion of ceramide (CER) into sphingosine and free fatty acids at acidic pH. CER plays an important role in intracellular sphingolipid met...

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Détails bibliographiques
Publié dans:FASEB J
Auteurs principaux: Bhat, Owais M., Yuan, Xinxu, Kukreja, Rakesh C., Li, Pin-Lan
Format: Artigo
Langue:Inglês
Publié: 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8221173/
https://ncbi.nlm.nih.gov/pubmed/34143450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202100385R
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