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Control of lysosomal TRPML1 channel activity and exosome release by acid ceramidase in mouse podocytes

The transient receptor potential mucolipin 1 (TRPML1) channel has been reported to mediate lysosomal Ca(2+) release that is involved in Ca(2+)-dependent lysosome trafficking and autophagic flux. However, this regulatory mechanism of lysosomal TRPML1 channel activity in podocytes remains poorly under...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Li, Guangbi, Huang, Dandan, Hong, Jinni, Bhat, Owais M., Yuan, Xinxu, Li, Pin-Lan
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6766620/
https://ncbi.nlm.nih.gov/pubmed/31268777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00150.2019
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