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Arterial Medial Calcification through Enhanced small Extracellular Vesicle Release in Smooth Muscle-Specific Asah1 Gene Knockout Mice

Arterial medial calcification (AMC) involves an increased small extracellular vesicle (sEV) secretion and apatite calcium precipitation in the arterial wall. The mechanisms mediating AMC remain poorly understood. In the present study, smooth muscle-specific acid ceramidase (Ac) gene knockout mice (A...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Bhat, Owais M., Li, Guangbi, Yuan, Xinxu, Huang, Dandan, Gulbins, Erich, Kukreja, Rakesh C., Li, Pin-Lan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997457/
https://ncbi.nlm.nih.gov/pubmed/32015399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58568-5
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