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Arterial Medial Calcification through Enhanced small Extracellular Vesicle Release in Smooth Muscle-Specific Asah1 Gene Knockout Mice

Arterial medial calcification (AMC) involves an increased small extracellular vesicle (sEV) secretion and apatite calcium precipitation in the arterial wall. The mechanisms mediating AMC remain poorly understood. In the present study, smooth muscle-specific acid ceramidase (Ac) gene knockout mice (A...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bhat, Owais M., Li, Guangbi, Yuan, Xinxu, Huang, Dandan, Gulbins, Erich, Kukreja, Rakesh C., Li, Pin-Lan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997457/
https://ncbi.nlm.nih.gov/pubmed/32015399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58568-5
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