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Medial calcification in the arterial wall of smooth muscle cell‐specific Smpd1 transgenic mice: A ceramide‐mediated vasculopathy

Arterial medial calcification (AMC) is associated with crystallization of hydroxyapatite in the extracellular matrix and arterial smooth muscle cells (SMCs) leading to reduced arterial compliance. The study was performed to test whether lysosomal acid sphingomyelinase (murine gene code: Smpd1)‐deriv...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Bhat, Owais M., Yuan, Xinxu, Cain, Chad, Salloum, Fadi N., Li, Pin‐Lan
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6933411/
https://ncbi.nlm.nih.gov/pubmed/31743567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.14761
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