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Long-range allostery mediates cooperative adenine nucleotide binding by the Ski2-like RNA helicase Brr2
Brr2 is an essential Ski2-like RNA helicase that exhibits a unique structure among the spliceosomal helicases. Brr2 harbors a catalytically active N-terminal helicase cassette and a structurally similar but enzymatically inactive C-terminal helicase cassette connected by a linker region. Both casset...
Shranjeno v:
| izdano v: | J Biol Chem |
|---|---|
| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2021
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8220420/ https://ncbi.nlm.nih.gov/pubmed/34048711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100829 |
| Oznake: |
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