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Investigating Tumor Heterogeneity in Mouse Models

Cancer arises from a single cell through a series of acquired mutations and epigenetic alterations. Tumors gradually develop into a complex tissue comprised of phenotypically heterogeneous cancer cell populations, as well as noncancer cells that make up the tumor microenvironment. The phenotype, or...

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Bibliografische gegevens
Gepubliceerd in:Annu Rev Cancer Biol
Hoofdauteurs: Tammela, Tuomas, Sage, Julien
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8218894/
https://ncbi.nlm.nih.gov/pubmed/34164589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-cancerbio-030419-033413
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