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Investigating Tumor Heterogeneity in Mouse Models

Cancer arises from a single cell through a series of acquired mutations and epigenetic alterations. Tumors gradually develop into a complex tissue comprised of phenotypically heterogeneous cancer cell populations, as well as noncancer cells that make up the tumor microenvironment. The phenotype, or...

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Detalhes bibliográficos
Publicado no:Annu Rev Cancer Biol
Main Authors: Tammela, Tuomas, Sage, Julien
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8218894/
https://ncbi.nlm.nih.gov/pubmed/34164589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-cancerbio-030419-033413
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