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Heterotypic mouse models of canine osteosarcoma recapitulate tumor heterogeneity and biological behavior

Osteosarcoma (OS) is a heterogeneous and rare disease with a disproportionate impact because it mainly affects children and adolescents. Lamentably, more than half of patients with OS succumb to metastatic disease. Clarification of the etiology of the disease, development of better strategies to man...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Scott, Milcah C., Tomiyasu, Hirotaka, Garbe, John R., Cornax, Ingrid, Amaya, Clarissa, O'Sullivan, M. Gerard, Subramanian, Subbaya, Bryan, Brad A., Modiano, Jaime F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5200896/
https://ncbi.nlm.nih.gov/pubmed/27874835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.026849
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