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Canine Osteosarcoma Cells Exhibit Resistance to Aurora Kinase Inhibitors
We evaluated the effect of Aurora kinase inhibitors AZD1152 and VX680 on canine osteosarcoma cell lines. Cytotoxicity was seen in all four cell lines; however, half-maximal inhibitory concentrations were significantly higher than in human and canine leukemia cells. AZD1152 reduced Aurora kinase B ph...
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| Publicado no: | Vet Comp Oncol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4672990/ https://ncbi.nlm.nih.gov/pubmed/23410058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/vco.12018 |
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