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Preclinical validation of Aurora kinases-targeting drugs in osteosarcoma
BACKGROUND: Aurora kinases are key regulators of cell cycle and represent new promising therapeutic targets in several human tumours. METHODS: Biological relevance of Aurora kinase-A and -B was assessed on osteosarcoma clinical samples and by silencing these genes with specific siRNA in three human...
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Κύριοι συγγραφείς: | , , , , , , , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
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Nature Publishing Group
2013
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3833226/ https://ncbi.nlm.nih.gov/pubmed/24129234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.643 |
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