Cisplatin Resistance in Osteosarcoma: In vitro Validation of Candidate DNA Repair-Related Therapeutic Targets and Drugs for Tailored Treatments

Treatment of high-grade osteosarcoma, the most common malignant tumor of bone, is largely based on administration of cisplatin and other DNA damaging drugs. Altered DNA repair mechanisms may thus significantly impact on either response or resistance to chemotherapy. In this study, by using a panel o...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Fanelli, Marilù, Tavanti, Elisa, Patrizio, Maria Pia, Vella, Serena, Fernandez-Ramos, Amira, Magagnoli, Federica, Luppi, Silvia, Hattinger, Claudia Maria, Serra, Massimo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7077033/
https://ncbi.nlm.nih.gov/pubmed/32211337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.00331
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