Arginase Treatment Prevents the Recovery of Canine Lymphoma and Osteosarcoma Cells Resistant to the Toxic Effects of Prolonged Arginine Deprivation

Rapidly growing tumor cells require a nutrient-rich environment in order to thrive, therefore, restricting access to certain key amino acids, such as arginine, often results in the death of malignant cells, which frequently display defective cell cycle check-point control. Healthy cells, by contrast...

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主要な著者: Wells, James W., Evans, Christopher H., Scott, Milcah C., Rütgen, Barbara C., O'Brien, Timothy D., Modiano, Jaime F., Cvetkovic, Goran, Tepic, Slobodan
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2013
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554772/
https://ncbi.nlm.nih.gov/pubmed/23365669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054464
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