METTL3 promotes tumour development by decreasing APC expression mediated by APC mRNA N(6)-methyladenosine-dependent YTHDF binding

The adenomatous polyposis coli (APC) is a frequently mutated tumour suppressor gene in cancers. However, whether APC is regulated at the epitranscriptomic level remains elusive. In this study, we analysed TCGA data and separated 200 paired oesophageal squamous cell carcinoma (ESCC) specimens and the...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Wang, Wei, Shao, Fei, Yang, Xueying, Wang, Juhong, Zhu, Rongxuan, Yang, Yannan, Zhao, Gaoxiang, Guo, Dong, Sun, Yingli, Wang, Jie, Xue, Qi, Gao, Shugeng, Gao, Yibo, He, Jie, Lu, Zhimin
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2021
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217513/
https://ncbi.nlm.nih.gov/pubmed/34155197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23501-5
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares