METTL3-mediated N(6)-methyladenosine mRNA modification enhances long-term memory consolidation

The formation of long-term memory is critical for learning ability and social behaviors of humans and animals, yet its underlying mechanisms are largely unknown. We found that the efficacy of hippocampus-dependent memory consolidation is regulated by METTL3, an RNA N(6)-methyladenosine (m(6)A) methy...

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Detalhes bibliográficos
Publicado no:Cell Res
Principais autores: Zhang, Zeyu, Wang, Meng, Xie, Dongfang, Huang, Zenghui, Zhang, Lisha, Yang, Ying, Ma, Dongxue, Li, Wenguang, Zhou, Qi, Yang, Yun-Gui, Wang, Xiu-Jie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6218447/
https://ncbi.nlm.nih.gov/pubmed/30297870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-018-0092-9
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