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Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development
Mechanical forces control cell behavior, including cancer progression. Cells sense forces through actomyosin to activate YAP. However, the regulators of F-actin dynamics playing relevant roles during mechanostransduction in vitro and in vivo remain poorly characterized. Here we identify the Fascin1...
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| Publié dans: | Commun Biol |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8217270/ https://ncbi.nlm.nih.gov/pubmed/34155338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02286-9 |
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